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sparsentan will lessen the level or influence of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and cuts down efficacy related to these substrates.It was clinically found that modafinil impacts pharmacodynamics of medicines that happen to be me